446 Avenue of the Americas

The city photographed every building for its tax records around 1940 and again in the 1980s. NYC Municipal Archives.

Written with AI from the source each entry cites, then fact-checked.

1845
Two more Greek Revival houses go up beside John H. Martine's corner pair
A second pair of Greek Revival houses on the lots, later numbered 446 and 448 Sixth Avenue, was completed in the mid-1840s, each with a store at street level. John H. Martine, who had bought the four lots in 1834, lived upstairs at No. 446. Around 1851 druggist George W. Delavergne moved his apothecary into the No. 446 storefront, partnering with Edward H. Andrew.
Source: Daytonian in Manhattan
1871
January 1
Thomas Macmahan buys the drugstore and later helps found a pharmacists' group
Thomas J. Macmahan, who had worked for the drugstore's earlier proprietor in the 1860s, became a partner of George G. Porter in 1870 and bought him out on January 1, 1871. In 1879 he was among the organizers of the New York State Pharmaceutical Association. Around then he sold the drugstore to go into manufacturing, and his best-known product was a tooth powder.
Source: Daytonian in Manhattan
1898
April 27
A Spanish-American War recruiting office enrolls 1,550 volunteers
In 1897 the ground-floor space, which had been a restaurant, was remodeled to house the Industrial Co-Operative Building and Loan Association's offices. After the Spanish-American War began, part of the offices was converted into a recruiting office. The Evening Post reported on April 27, 1898 that 1,550 volunteers for William Astor Chanler's regiment had been enrolled there and were having medical examinations.
Source: Daytonian in Manhattan

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